3. To cause overexpression of the genes it controls, would MECP2 protein have to remove methyl...
3. To cause overexpression of the genes it controls, would MECP2 protein have to remove methyl groups, or stabilize them?
Homework Answers
Answer
To cause overexpression of the genes it controls, MECP2 protein has to remove methyl group so that it can not bind with CpG iland as MECP2 is known as a transcriptional repressor. If there is less or no methylation of CpG iland of any target gene then MECP2 will not be able to find that region as a result oversexpression of gene will happens.
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