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What type of cell death is most often induced in cancer cells by radiation and chemotherapy...

What type of cell death is most often induced in cancer cells by radiation and chemotherapy drugs? Why is this? (ie- which factor is often missing in cancer cells?)

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Answer #1

Chemotherapy is used to kill the cancerous cells and reduce the tumors. It is used to destroy the cell division control center. Chemotherapy mainly targets the fast dividing cells and we know that the cancerous cells divide rapidly. So it leads to apoptosis of cancer cells.

The reasons behind uncontrolled growth of cancerous cells are-

-Lack of contact inhibition in which a cell stops to divide when come in contact with adjacent cells.

-Due to presence of telomerase enzyme.

- lack of tumor protein p53 which is required at checkpoint.

Thanks.

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