Question

Support the hypothesis that signaling pathways appeared early in evolution and are well-conserved using the yeast mating factor as an example.

A) Signaling in yeast uses the RTK pathway and is evolutionarily conserved, like epinephrine signaling in humans.

B) Signaling in yeast uses G-protein coupled receptors for signaling and is evolutionarily conserved, like epinephrine signaling in humans.

C) Signaling in yeast uses an endocrine pathway and is evolutionarily conserved, like epinephrine signaling in humans.

D) Mating factor in yeast uses an autocrine signaling pathway and is evolutionarily conserved, like epinephrine signaling in humans.

Answer 1

Support the hypothesis that signaling pathways appeared early in evolution and are well-conserved using the yeast mating factor as an example. The correct option is B.

B) Signaling in yeast uses G-protein coupled receptors for signaling and is evolutionarily conserved, like epinephrine signaling in humans.

The G-coupled receptor signaling pathway mediates the mating response in yeasts and this fact has been widely used for conducting studies of GPCR function in mammals the past.