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How does Blood Doping affect the endocrine, nervous system, excretory system? How does Blood Doping work?

How does Blood Doping affect the endocrine, nervous system, excretory system?

How does Blood Doping work?

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ANS 1) BLOOD DOPING METHOD- Blood doping is a method of improving the athletic performance by artificial boosting the blood ability to bring more oxygen to muscles.

affect of blood doping on the endocrine system -

The endocrine glands plays an important role in hemostasis and controlling the various activities in the body by secreting the hormone. The endocrine glands are also called as the ductless glands because the hormones secreted by them are realized directly into the blood,where the actions need to be executed.

1)exercise training- stimulates release of certain hormones that support favourable adaptive changes.for example it is a major stimulator of growth hormone, growth hormone is responsible for all the tissues, increase in the size and no. By increasing the mitotic division. hypersecreation of growth hormone leads to gigantism. (Hcg) human growth hormone may make muscles and bone stronger a protruding head, skull and jaw, an enlarged heart , damage to liver,thyroid and vision,bigger joints leading to arthritis.

2) the case of doping with growth hormone, erythropoietin and metabolic steroids- due to the hyperactivity of the growth hormone it can mismatch the feedback control system and leads to the gigantism, it is a pituitary disorder characterized by the ecsses growth of the body,general over growth and development of huge stature with a height of 7 to 8 feet.

3) substances on the name of doping used- anabolic agents(exogenous and endogenous),peptide hormones ,erythropoietin stimulating agents,beta blockers , cannabinoids,glucocorticoids .

4) anabolic steroids use has been linked with harm full effects,ranging in severity from largely cosmetic acne to life threatening heart attack.it can also result in profound changes in mood and can increase aggressive behavior, extra side effects - shrinking testicles, breast growth in males, impotence, deeper voice in females, excessive body hair in females, abnormal menstrual cycles.

5) blood transfusion illicit blood transfusions are used by athletes to boost performance. In this there is a high risk of blood infection.

6) EPO- may help you to uses oxygen. But by risking your life,feeling week,an increase in bp,leading to heart stroke or collapse .

on nervous system -

Nervous system controls all the activities of the body, it is quicker than the other control system of the body .

1) Cns stimulates can be used to reduce tiredness, and increase alertness,competition and agression. Three main cns stimulates ephedrine, amphetamine , and cocaine in relation to misuse in sports.

2) central nervous system stimulates were used by the athletic to improve performance on the day of competition they might lead to collapse and sudden death.usually from a cardiac or the respiratory arrest.

3)long term use might lead to addiction and physiological disturbances.

4)caffeine is also taken as a stimulant effects include increased heart rate , anxiety, insomnia, and nervous ness.

5) amfetamines are the controlled substances under .they are known to produce dependence, high bp, difficult to the body to cool down.

on excretory system-

Some of the athletic uses the masking agents by using diuretics. There are a certain side effects -

Dizziness or light heaviness

Low blood pressure

Loss of coordination and balance

Development of cardiac disorders

exercise intensive- it induces profound changes in the renal hemodynamic and in electrolyte and protien secretion.

how does blood doping works?

methods

1)drug treatment- (EPO) erythropoietin

hypoxia induced factor

2)blood transfusion

3)blood substitute

4)hemoglobin based oxygen carriers

5)cocaine marijuana

these drug treatments are used to enhance oxygen delivery when the human body can't do it naturally.

erythropoietin increases the activity of a hemocytoblast allows the blood to have a greater carrying capacity for oxygen.

hif stabilizer responsible for the expression of a protien.creation of new blood vessels.

blood transfusions begins by the withdrawal of 1 to 4 ml of blood several weeks before the competition. The blood is centrifugal, the plasma components are immediately reused, and the red blood cells are reused.

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