Question

The sex determination mechanism of mice is similar to that of humans, with one notable exception: mice that are XO aneuploids are functional females.

1. In a mating of an XO female with a normal male, what genotypic and phenotypic ratios would you expect in the offspring?

2.  If an XXY mouse were fertile, what genotypic and phenotypic ratios would result from a mating between an XO female and an XXY male?

Answer 1

Answer 1 if female has genotype XO then gametes forms will have only half X and half O [no sex chromosome], while male gametes have X and Y

So the resulting offsprings

	X	O
X	XX	XO
Y	XY	YO [infertile]

2 Male has genotype XXY and female genotype is XO then resulting offspring

	X	O
X	XX	XO
X	XX	XO
Y	XY	YO