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What would happen if the Cas9 part of CRISPR-Cas9 wasn't functional? Would CRISPR be as effective?

What would happen if the Cas9 part of CRISPR-Cas9 wasn't functional? Would CRISPR be as effective?

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Answer #1

Answer: No
Explanation:
Cas9 is an RNA guided DNA endonuclease. It recognizes a specific DNA sequence and cleaves it.
The target specificity is attained through the complementary sequence of the guide RNA.
dCas9 is an endonuclease deficient Cas9 that is used for transcriptional gene sl=ilencing of specific genes.

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