Ibuprofen is a weak acid with a solubility in water of 21 mg/L and a pKa of 4.91. What is the pH of a saturated solution of ibuprofen in water? The chemical formula of ibuprofen is C13H18O2.
Ibuprofen is a weak acid with a solubility in water of 21 mg/L and a pKa...
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Ibuprofen, a non-steroidal anti- inflammatory drug, is a weak acid with pKa of 5.2. The structure of ibuprofen is shown below. 2. bosiccare. Compare tor ibuprofen ablets 200 mg Reducer NAD) 500 COATED TABLETS a. What is the pH when 150 mL of 0.4 M NaOH is added to 150 mL of 1.5 M ibuprofen solution? b. What is the pH when 150 mL of 1.5M ibuprofen solution is added to 5L of water?
Phenytoin is an extremely weak acid, pKa 8.3, with very poor water solubility. Solubility of the sodium salt in water is 15 g/L, and in ethanol it is 95 g/L. It is freely soluble in warm propylene glycol and it has a molecular weight of 274.3. We are going to prepare five 5 mL vials of this product. With its poor water solubility, how would you propose that the required concentration of 50 mg/mL be achieved and which and how...
Phenobarbital is a weak acid. Its intrinsic solubility is 1g /L. Its pKa is 7.4 and Mol Wt : 232.32 Calculate the pH of the buffer required to prepare a clear homogeneous solution.of phenobarbital 1 g/100 mL.
Omeprazole has a pKa value of 7.1. Is Omeprazole a weak acid or weak base? Circle the acidic or basic functional group in the structure 2. Calculate the percentage of omeprazole in the neutral form (non-ionized) in stomach (pH 1.5) and small intestines (pH 6.5). 3. What would you expect the pKa value of the carboxylic acid group in the derivatized omeprazole? Is the derivatized omeprazole an acid, base or something else? 4. Explain why the omeprazole derivative may have...
PART A. Determine the pH of a 9.553 mM weak acid solution that has a pKa of 8.83 PART B. Calculate the pH of a 319 mM weak base solution with a pKb of 9.04. PART C. Determine the pKa of a weak acid solution that has an initial concentration of 0.334 M and a pH of 4.54. Hint: You know the pH of the solution, so you can easily determine x in your ICE table PART D. Calculate the...
In a solution of the weak acid DNP (pKa 4.11) in water, [H3O+] = 9.4 x 10^-4 M and DNX, the conjugate base, has a concentration of 0.00180 M. A.) What is the concentration of DNP in the above solution? B.) What is the pH of the solution?
A 0.27 −mol sample of a weak acid with an unknown pKa was combined with 12.0 mL of 2.80 M KOH and the resulting solution was diluted to 1.500 L. The measured pH of the solution was 3.85. What is the pKa of the weak acid? Express your answer using two decimal places.
Calculate and compare the molar solubility of Mg(OH)2 in water and in a solution buffered at a pH of 4.5. Part 1: (a) Determine the molar solubility of Mg(OH)2 in water and the pH of a saturated Mg(OH)2 solution. molar solubility =1.39 × 10^-4 M pH = 10.45 Part 2 out of 3 (b) Determine the molar solubility of Mg(OH)2 in a solution buffered at a pH of 4.5. molar solubility =_____× 10_____M
You dissolve 25.19 mg of arsenious acid (H3ArO3 , F.W. = 125.94) in 1.00 L of water. Arsenious acid is weak, with Ka = 5.1 × 10−10. Calculate the equilibrium concentrations of H3AsO3 and H2AsO – 3 and the pH of the solution. Assume that the activity coefficients are all 1, but you must include the autoprotolysis of water.
4. (15) A saturated solution of phenol, C6H5OH, a very weak acid with pKa=10.00, has pH=4.90. What is the molarity of phenol in this solution?