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A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is...

A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is 7. a. If the ([NAD+]/[NADH]) = 1.0, what is the concentration of pyruvate at equilibrium? b. If the glucose concentration in the muscle tissue is 3.5 mM at pH 7, what ratio of ([ATP]/[ADP]) is maintained in the muscle tissue at equilibrium?

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Answer #1

a. GLUCOSE    2 PYRUVATE 2 LACTATE

Since, 2 molar lactate is formed from 2 molar pyruvate, to form 2.5 mM lactate, the cell must contain 2.5 mM pyruvate.

b. In every cycle, ratio of ATP and ADP is 1.

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