some substrates for glutathione S-transferase don't form a glutathione conjugate as the product of the glutathione...
some substrates for glutathione S-transferase don't form a glutathione conjugate as the product of the glutathione S-transferase and glutathione-dependent reaction, what are some examples ?
Homework Answers
Some substrates for glutathione S-transferase don't form a glutathione conjugate as the product of the glutathione S-transferase and glutathione-dependent reaction.
First example-
Reaction of maleylacetoacetate and maleylacetone which is get isomerized into fumarylacetoacetate and fumarylacetone by glutathionetransferase.
Second example-
Reaction of androst-5-ene-3,17-dione and phenylalanine. The enzyme glutathione S-transferase isomerize the androst-5-ene-3,17-dione to androstenedione.
Both the reaction show no consumption of glutathione S-transferase in the reaction.
Thanking you
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