Alanine is an allosteric inhibitor of liver pyruvate kinase. What might be the reason? In choosing...
Alanine is an allosteric inhibitor of liver pyruvate kinase. What might be the reason? In choosing your answer consider the role of alanine in the glucose-alanine cycle.
Select one:
a. It reduces the amount of ATP available for the urea cycle.
b. It reduces the availability of pyruvate as an acceptor for the amino-groups derived from alanine.
c. It reduces the use of phosphenolpyruvate in glycolysis.
d. It increases the synthesis of glycerol-3-phosphate for fat biosynthesis.
e. It reduces the generation of acetyl-CoA to reduce mitochondrial ATP production.
Homework Answers
- It reduces the use of phosphenolpyruvate in glycolysis. (as pyruvate kinase acts in the conversion of PEP into pyruvate)
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