People with beriberi, a disease caused by a thiamin deficiency, have elevated levels of blood pyruvate...
People with beriberi, a disease caused by a thiamin deficiency, have elevated levels of blood pyruvate and α-ketoglutarate, especially after consuming a meal rich in glucose. How can you explain the rise in these compounds based on this vitamin?
Homework Answers
Thiamine pyrophosphate (TPP), the active form of thiamine, is a cofactor ( Non protein part of an enzyme) for enzyme Pyruvate dehydrogenase complex and alpha-ketoglutarate dehydrogenase. These enzyme play an important role in Krebs cycle. So people with vitamin B deficiency cannot synthesized TPP so they have elevated levels of blood pyruvate and α-ketoglutarate.
Thiamine-------> TPP is cofactor for -----> Pyruvate dehydrogenase and alpha ketoglutarate enzyme
No Thiamine----> No TPP----> Elevated Pyruvate and alpha ketoglutarate level
Add Answer to:
People with beriberi, a disease caused by a thiamin deficiency,
have elevated levels of blood pyruvate...
9.) (4 pts) A thiamine deficiency causes the disease beriberi. The symptoms are pain in the...
9.) (4 pts) A thiamine deficiency causes the disease beriberi. The symptoms are pain in the limbs, weakness of the muscles and distorted skin sensations. The heart becomes enlarged and the cardiac output diminishes. (a) Which of the metabolic pathways that we have studied would be affected by a thiamine deficiency? List the affected enzymes. Pyruvate dehydrogenasc (b) A deficiency of thiamine elevates the blood levels of pyruvate and a-ketoglutarate. How are these effects related to the deficiency? boldog
QUESTION 1 Which of the following is an advanced form of thiamin deficiency seen in alcoholics?...
QUESTION 1 Which of the following is an advanced form of thiamin deficiency seen in alcoholics? a. Scurvy b. Megaloblastic anemia c. Wernicke-korsokoff syndrome. d. Pellagra QUESTION 2 Which of the following is NOT TRUE about thiamin? a. A deficiency is called beriberi. b. Polyneuritis is a symptom of thiamin toxicity. c. Thiamin deficiency is common among people who subsist almost exclusively on white rice. d. Lean pork is a nutrient-dense source of naturally occurring thiamin. QUESTION 3 Which of...
6. Which group of people in the U.S. is most at risk for thiamin deficiency? Why?...
6. Which group of people in the U.S. is most at risk for thiamin deficiency? Why? 7. What is the name of the thiamin deficiency disease? 8. What are the major symptoms of thiamin deficiency? 9. Which food group contributes the most riboflavin to the diet in the United States? 10. What is the primary source of vitamin D for humans in general? 11. The body can make niacin from the amino acid ___________________________. What does your body generally do...
The people of Malaysia belong to three communities: the local people called Malays, immigrants from South...
The people of Malaysia belong to three communities: the local people called Malays, immigrants from South India called Tamils, and immigrants from China. During the early 20th century, the Malays lived mainly in coastal villages, the Tamils worked on rubber estates, and the Chinese worked in tin mines. In general, the people were very poor and they consumed a limited variety of foods.[1] Rice was the staple diet of all three communities and therefore the key source of caloric and...
Questions 1. Thiamin deficiency was observed only in the Chinese community even though all three communities...
Questions 1. Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the 2. rice should not be washed before cooking. Explain. deficiency. Explain. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 3. Severe metabolic acidosis caused by high levels of lactate is often associated with thiamin 4....
Questions Thiamin deficiency was observed only in the Chinese community even though all three communities had...
Questions Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. 1. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the rice should not be washed before cooking. Explain. 2. evere metabolic acidosis caused by high levels of lactate is often associated with thiamin deficiency. Explain. 4. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 5....
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C....
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C. when there is a deficiency of BOTH pyruvate and oxygen D. for the regeneration of NADH so that hydrolysis of ATP can continue to fuel the glycolysis pathway Explain how gluconeogenesis differs from gtycolysis 21 Gluconeogenesis is simply the reverse of all 10 steps...
Phenylketonuria is an inherited disease caused by a recessive allele. People with PKU can't break down...
Phenylketonuria is an inherited disease caused by a recessive allele. People with PKU can't break down the amino acid phenylalanine properly; this compound and a byproduct can accumulate in the blood to toxic levels, causing mental retardation. A man and a woman are both normal, but they are carriers of the disease. A) If they have children together, what proportion of the kids would be expected to have PKU? B) What proportion of their children would be normal?
Consuming too much of vitamin C has serious consequences (True/False). Vitamin C deficiency is called? Where can yo...
Consuming too much of vitamin C has serious consequences (True/False). Vitamin C deficiency is called? Where can you find beta-carotene? What is the difference between carotenoids and retinoids? Cancer is caused by free radicals; therefore, consuming antioxidants could help in preventing cancer True/False) List the nutrients involved in bone healthーーーーーーーーーーーーーーーーー , and Almost 100% of calcium consumed will be absorbed by the body (True/False) Chronic deficiency of calčum that causes some (especially the elderly) to have weak and brittle bone...
26. Why did Jessie’s carnitine deficiency cause her to have abnormally low plasma glucose levels at the end of a fasting...
26. Why did Jessie’s carnitine deficiency cause her to have abnormally low plasma glucose levels at the end of a fasting study, when compared to a healthy person who has fasted for the same length of time? In the absence of carnitine, the liver stores large amounts of glycogen; absorption of glucose to create these stores depletes blood glucose Carnitine acts as a hormone and stimulates glucose release from the liver; lack of carnitine results in loss of hepatic glucose...
9.) (4 pts) A thiamine deficiency causes the disease beriberi. The symptoms are pain in the limbs, weakness of the muscles and distorted skin sensations. The heart becomes enlarged and the cardiac output diminishes. (a) Which of the metabolic pathways that we have studied would be affected by a thiamine deficiency? List the affected enzymes. Pyruvate dehydrogenasc (b) A deficiency of thiamine elevates the blood levels of pyruvate and a-ketoglutarate. How are these effects related to the deficiency? boldog
Questions 1. Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the 2. rice should not be washed before cooking. Explain. deficiency. Explain. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 3. Severe metabolic acidosis caused by high levels of lactate is often associated with thiamin 4....
Questions Thiamin deficiency was observed only in the Chinese community even though all three communities had the same staple (rice) diet. Explain. 1. On packages of enriched rice sold in supermarkets, the rice preparation directions state that the rice should not be washed before cooking. Explain. 2. evere metabolic acidosis caused by high levels of lactate is often associated with thiamin deficiency. Explain. 4. Provide two plausible explanations for what might cause above normal levels of pyruvate in blood 5....
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C. when there is a deficiency of BOTH pyruvate and oxygen D. for the regeneration of NADH so that hydrolysis of ATP can continue to fuel the glycolysis pathway Explain how gluconeogenesis differs from gtycolysis 21 Gluconeogenesis is simply the reverse of all 10 steps...
Consuming too much of vitamin C has serious consequences (True/False). Vitamin C deficiency is called? Where can you find beta-carotene? What is the difference between carotenoids and retinoids? Cancer is caused by free radicals; therefore, consuming antioxidants could help in preventing cancer True/False) List the nutrients involved in bone healthーーーーーーーーーーーーーーーーー , and Almost 100% of calcium consumed will be absorbed by the body (True/False) Chronic deficiency of calčum that causes some (especially the elderly) to have weak and brittle bone...
Most questions answered within 3 hours.
-
Where is the error in this code sequence?
String s1 = "Hello";
String s2 = "ello";...
asked 10 months ago -
Financial data for Joel de Paris, Inc., for last year
follow:
Joel de Paris, Inc.
Balance...
asked 10 months ago -
Consider this reaction:
Al2(SO4)3 (aq)+ BaCl3
(aq) Al2Cl6 (aq)- +
3BaSO4(s) . What is the...
asked 10 months ago -
Suppose that Savneet is considering increasing her
recent random sample from 20 car rentals to 40...
asked 10 months ago -
Trucks arrive at an unloading terminal at an average rate of 120
per hour.
Trucks arrive...
asked 10 months ago -
Why are methanol and ethanol completely soluble in water while
octanol is not very little soluble....
asked 10 months ago -
A facilities manager at a university reads in a research report
that the mean amount of...
asked 10 months ago -
When the CuSO4 is rehydrated by adding water to the anhydrous
compound, is this an endothermic...
asked 10 months ago -
A ray of sunlight is passing from diamond into crown glass; the
angle of incidence is...
asked 10 months ago -
A block of mass 0.249 kg is placed on top of a light, vertical
spring of...
asked 10 months ago -
how do the kidneys compensate in the presences of acidosis
a) trigger hyperventilate
b) reserve acid...
asked 10 months ago -
Question 501 pts
The rental rate of capital to the firm increases. Which of the
following...
asked 10 months ago