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What proteins are involved in the transition of G0 to G1in the cell cycle? ( I...

What proteins are involved in the transition of G0 to G1in the cell cycle? ( I know P53 is one but am having trouble finding the others)

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There are several proteins which are required for the transition of G0 to G1 phase in the cell cycle. G0 phase is also known as quiescent state. Here cells are temporarily in a rest position, preparing for cell division . G1 phase is also known as growth phase of the cell. Enzymes are synthesized for DNA replication at this stage. Here, p53 and Rb gene are the main controlling proteins. In addition to p53 and Rb, there are other proteins too namely p21, p27,p57 which also play a part in the transition phase. Phosphorylation of Rb protein and knockout of p57 and p21 protein is necessary for the cell to exit the G0 phase.

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