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Why do almost all drugs of abuse increase locomotor activity in rodents?

Why do almost all drugs of abuse increase locomotor activity in rodents?
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Answer: Drug abuse such as the administration of cocaine, morphine, etc when introduced into the body of rodents (the group of mammals who possess ever-growing rootless incisor teeth examples includes: mice, rabbits, hares etc.) indicates the neuronal activity. This activity generally increases and stimulates certain channel receptors in the brain making brain certain regions overreactive and which further increases the activity of locomotory organs in mammals.

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Why do almost all drugs of abuse increase locomotor activity in rodents?
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