A 25-year-old man received five units of group O, D-negative RBCs in the emergency room after...
A 25-year-old man received five units of group O, D-negative RBCs in the emergency room after a serious car accident. His blood type, which was determined from a sample collected before transfusion, was group O, D-negative. A sample was resubmitted 2 weeks after the accident for pretransfusion before orthopedic surgery. The antibody screen was positive, and the antibodies identified were anti-D and anti-C.
- What are the possible explanations for the antibodies identified?
- What additional testing should be performed to explain the problem?
- If the blood type of the units he received was correct, what is the probable Rh phenotype of the units that he received?
- What antigen or antigens should be negative if he needs RBC transfusions in the future?
- Based on your knowledge of Rh antigen frequency, will it be difficult to obtain these units?
Homework Answers
Answer 1. The person has not received correct blood type due to which he sufferef from acute hemolytic transfusion reaction.
Answer 2- Direct and indirect coombs test should be performed with donors blood again to test the blood type.
Answer-3 Rh positive
Answer- 4 Rh negative and O negative bllod groups should be given
Answer-5 yes it will be difficult to obtain as only 7% of the populaion has this bllod group
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A 25-year-old man received five units of group O, D-negative
RBCs in the emergency room after...
Background INFO There are four types of blood: A, B, AB, and O (Figure 4). Each...
Background INFO
There are four types of blood: A, B, AB, and O (Figure 4). Each
is characterized by the glycoproteins (proteins with a sugar
attached) and lipoproteins (proteins with a lipid attached)
embedded in the surface of red blood cells (RBCs). In addition to
type, blood can be rhesus (Rh) factor positive or negative.
These proteins are inherited and may differ from individual to
individual. If, during a transfusion, an individual receives
blood with the incorrect RBC proteins (for...
A 55-year-old man is admitted to the emergency department after a motor vehicle accident. The patient...
A 55-year-old man is admitted to the emergency department after a motor vehicle accident. The patient is hemorrhaging from a lacerated spleen and requires emergency surgery. Pretransfusion testing determines that the patient’s phenotype is group A, D-negative type with a negative antibody screen. Crossmatches with red blood cell units are compatible by the immediate-spin crossmatch. During surgery, the patient receives 6 units of group A, D-negative red blood cells and 4 units of group A frozen plasma. Three days later,...
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History: V is a 52-year old woman who just underwent surgery that resulted in the need to transfuse two units of red blood cells. V has three children and has reported to have been transfused twice in...
History:
V is a 52-year old woman who just underwent surgery that
resulted in the need to transfuse two units of red blood cells. V
has three children and has reported to have been transfused twice
in the past.
6. Which of the
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identification (completion of panel antigram)? (2 pts)
A.
Anti-Jsa
B.
Anti-Lub
C. Anti-e
D.
Anti-Jkb
7. Given the
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Urinalysis Case 6-5 Sean F., a 25-year-old man, was brought to the emergency room with severe...
Urinalysis Case 6-5 Sean F., a 25-year-old man, was brought to the emergency room with severe crush injuries sustained in a car accident. He had a broken pelvis and right femur and numerous abrasions and contusions. A routine urinalysis was ordered as part of the regular preoperative blood work. (sce Table 6-5). Table 6-5 Urinalysis and Chemistry Urinalysis Sean F. Reference Range Macroscopic Color Appearance Specific gravity Brown Clear Colorless to amber Clear 1.001-1.035 5-7 1.013 6.0 pH Nes Protein...
Question: The whole process before administering blood can be broken down into the following nine activities:...
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Which electrolyte measurement is least affected by hemolysis? a. Calciumb. b- Magnesium c. Potassium d. Total...
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Background INFO
There are four types of blood: A, B, AB, and O (Figure 4). Each
is characterized by the glycoproteins (proteins with a sugar
attached) and lipoproteins (proteins with a lipid attached)
embedded in the surface of red blood cells (RBCs). In addition to
type, blood can be rhesus (Rh) factor positive or negative.
These proteins are inherited and may differ from individual to
individual. If, during a transfusion, an individual receives
blood with the incorrect RBC proteins (for...
History:
V is a 52-year old woman who just underwent surgery that
resulted in the need to transfuse two units of red blood cells. V
has three children and has reported to have been transfused twice
in the past.
6. Which of the
following antibodies remain after completion of the antibody
identification (completion of panel antigram)? (2 pts)
A.
Anti-Jsa
B.
Anti-Lub
C. Anti-e
D.
Anti-Jkb
7. Given the
patient history and all serology results, what is the best
hypothesis...
Urinalysis Case 6-5 Sean F., a 25-year-old man, was brought to the emergency room with severe crush injuries sustained in a car accident. He had a broken pelvis and right femur and numerous abrasions and contusions. A routine urinalysis was ordered as part of the regular preoperative blood work. (sce Table 6-5). Table 6-5 Urinalysis and Chemistry Urinalysis Sean F. Reference Range Macroscopic Color Appearance Specific gravity Brown Clear Colorless to amber Clear 1.001-1.035 5-7 1.013 6.0 pH Nes Protein...
26% -), AT&T LTE 10:08 AM Capstone Case Studies.. Case Study and Questions A 65-year old man entered the emergency department of a local hospital. He appeared to be acutely ill with abdominal tenderness and a temperature ef 40" C. The patient was taken to urpery because appendicitis was suspected. A ruptured appendix surounded by 20 ml of foul-smelling pus was Sound at laparotomy. The pus was drained and submitied Sor acrobic and anacrobie bacterial culture analysis. Postoperatively, the patient...
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