Salmonella enterica is a species of bacteria that can infect the gastrointestinal tract. Its LPS is hyper immunostimulatory. Given that most of the microbiota of the GIT are obligate anaerobes, describe how this infection (providing the Salmonella can survive the immune response) can cause enteritis (intestinal inflammation) that is hard to resolve (feedforward inflammation)?
Salmonella enterica is a species of bacteria that can infect the gastrointestinal tract. Its LPS is...
34) During Salmonella enterica gastroenteritis (acute inflammation of the stomach and intestines, often accompanied by nausea, vomiting, diarrhea, and abdominal pain), responding neutrophils of the human immune system generate an oxidizing environment that generates tetrathionate, a compound Salmonella uses as a terminal electron acceptor for anaerobic respiration. Most normal microbiota are unable to use this compound, instead relying on fermentation in this anaerobic environment. In the densely populated intestinal tract, this . A) slows the growth of Salmonella relative to...
Part I – Background on Salmonella Salmonellosis is a gastrointestinal illness caused by bacteria from the genus Salmonella. The illness is characterized by the sudden onset of headache, abdominal pain, diarrhea (which may be bloody), nausea, and sometimes vomiting. Fever is almost always present. The illness typically lasts for 5-7 days and usually does not require treatment unless the patient becomes severely dehydrated or the infection spreads from the intestines. In the immune compromised host or an overwhelming infection in...