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Can a B cell synthesize both integral-membrane Ig and secreted Ig at the same time? explain...

Can a B cell synthesize both integral-membrane Ig and secreted Ig at the same time? explain briefly

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B cell can synthesize both integral membrane Ig and secreted Ig.

First formed Ig is the membrane bound. It gets incorporated in the plasma membrane. There are 105 such receptors. It has unique antigen binding site. Single species of antibody is secreted by a particular B cell.

When the antigen comes, the memory B cell become active and proliferates into an antibody secreting effector cell with help of helper T cell. It secretes the soluble Ig. It has the same unique antigen binding site as the cell surface Ig.

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