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What kind of T cells respond to class I MHC proteins presented by almost all body...

What kind of T cells respond to class I MHC proteins presented by almost all body cell types?

What general term is used to describe a range of peptide and protein chemical signals, such as the interleukins, tumor necrosis factor, and the interferons?

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Answer #1

"Helper T cells" react with antigens presented on the surface of macrophages or oJher cells, complexed with MHC Class II molecuIes.

They are called Cytokines they are biologically active substances released by activated T lymphoctyes are called lymphokines.

Examples of lymphokines

I. Affecting macrophages.

a) Migration inhibiting factor (MIF)

b) Macrophage activation/Aggregation factor (MAF)

c) Macrophage chemotactic factor (MCF)

II. Affecting lymphocytes

a) Blastogenic/Mitogenic factor (BF/MF) b) T cell growth factor (TGF)

c) B cell growth factor (BGF)

Ill. Affecting granulocytes

a) Chemotactic factor (CF)

b) Colony stimulating factor (CSF)

IV. Affecting cultured cells

a) Lymphotoxin (LT)

b) Interferon (IFN)

c) Tumour necrosis factor (TNF)

V. Others

a) Skin reactive factor (SRF)

b) Transfer factor (TF)

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