Adding acetyl groups to histone tails _____ the interaction between the histones and DNA. a) weakens...
Adding acetyl groups to histone tails _____ the interaction between the histones and DNA.
a) weakens
b) strengthens
Homework Answers
Adding acetyl groups to histone tails weakens the interaction between the histones and DNA. Deacetylation of the histones leads to tight bonding between DNA and histones which makes the DNA less accessible to transcription factors due to which expression decreases.
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Adding acetyl groups to histone tails _____ the interaction
between the histones and DNA.
a) weakens...
Which of the following is not true of histone tails? They are capable of automodifications (they...
Which of the following is not true of histone tails? They are capable of automodifications (they can modify themselves). They protrude between the two DNA strands that supercoil around the nucleosome. They experience changes in net charge, shape, and other properties of histones in response to modifications. They are recognized by acetylases and methylases
Identify the most accurate term related to chromatin remodeling. DNA is associated with proteins to form....
Identify the most accurate term related to chromatin remodeling. DNA is associated with proteins to form. A is compsed of DNA wrapped around an octamer of histone proteins. An activator can increase transcription by attracting a to the region. Addition of (-COCH_3) groups to histone amino terminal tails results in a/an in gene expression. Removal of acetyl groups from histones results in a/an in gene expression.
What is the common between histone proteins and spermiding? 1.)histones and spermidine are present only in...
What is the common between histone proteins and spermiding? 1.)histones and spermidine are present only in bacteria. 2.)histones are spermidine are negatively charged 3.) histones are spermiding help DNA attain a random coil conformation 4.) they both play a role in DNA packaging Which of the following factors makes hydrolysis of acetyl coA a favorable process? 1.)separation of like charges 2.)increased delocalization of the pi-cloud 3.)enol-keto tautomerication 4.) change of non-aromatic structure to aromatic structure The amino acid responsible for...
3. Which of the following is not a good example of a housekeeping protein in eukaryotic...
3. Which of the following is not a good example of a housekeeping protein in eukaryotic cells? a)DNA polymerase b)histones c)RNA polymerase 4)hemoglobin Explanation: 4. Which of the following statements about histones is true? a. Histones activate transcription when bound to the promoter, b. Although RNA polymerase can access DNA packed around histones, the general transcription factors and transcriptional regulators cannot. c. Histone acetyltransferases affect transcription by adding acetyl groups to histones and altering chromatin structure to allow accessibility to...
Histone de-acetylases prevent further gene expression in which of the following ways? Restoring the charge attraction...
Histone de-acetylases prevent further gene expression in which of the following ways? Restoring the charge attraction between histones and DNA Preventing transcription factor binding Lessening the charge attraction between histones and DNA Adding a chemical tag to the DNA that silences it
3. Persistence length of DNA and energy cost of bending DNA around histone proteins (a) DNA is st...
3. Persistence length of DNA and energy cost of bending DNA around histone proteins (a) DNA is stiff because it is a double helix. At room temperature in dilute solution the persistence length of DNA is found to be p-50 nm. Using this persistence length, find the bending spring constant of DNA (b) In chromosomes, DNA molecules are wrapped tightly around histones. Consider wrapping a DNA molecule around a full circle, estimate the energy cost of bending DNA around the...
Question 5 QUESTION 2 What is common between histone proteins and spermidine? Histones and Spermidine are...
Question 5
QUESTION 2 What is common between histone proteins and spermidine? Histones and Spermidine are negatively charged. Histones and spermidine help DNA attain a random coil conformation They both play a role in DNA packaging. Histone and spermidine are present only in bacteria. QUESTION 3 Which of the following is NOT is product of Kreb's cycle NAD+ ATP FADH2 CO2 QUESTION 4 The amino acid responsible for introducing kinks in DNA helical structure by intercalation is Phenylalanine Ethidium Bromide...
You are interested in the interactions of histone deacetylase (HDAC) with nucleosomes. Using a DNA template...
You are interested in the interactions of histone deacetylase
(HDAC) with nucleosomes. Using a DNA template that is end labelled
with 32P and has two nucleosomes already bound to it, you perform a
gel-shift experiment with HDAC and the chromatin from above. You
also assemble chromatin with nucleosomes that have been methylated
at a particular amino acid residue of Histone H4. The results are
below. Based on the data, (A) explain the autoradiogram below –
what are all the bands?...
which if the following best describes the mechanism by which chromatin remodeling complexes loosen the dna...
which if the following best describes the mechanism by which chromatin remodeling complexes loosen the dna wrapped around the core histones A) they chemical lie modify the DNa changing the affinity between the histones octaves and the DNA B) they use energy derived from ATP hydrolysis to change the relative position of the Dan and the core histone octamer C) they remove histone H1 from the linker DNA adjacent to the core histone octamer
ton is not an energy dependent process in (B)) Falls eukaryotes 43. Histone methylation is associated...
ton is not an energy dependent process in (B)) Falls eukaryotes 43. Histone methylation is associated with Falls gene activation gene silencing Following histones are required during transcription (A) H2A and 2B (B) H3 (C) H4 (D) All of the above (E) H2AZ (c) induction (D) All of the above (E) None of the above 35. 4. DNA methylation silences gene expression AD True (B) Fall Leucine residues in lucine zipper proteins provides h ydrophobic interaction for dimerization (A) True...
Identify the most accurate term related to chromatin remodeling. DNA is associated with proteins to form. A is compsed of DNA wrapped around an octamer of histone proteins. An activator can increase transcription by attracting a to the region. Addition of (-COCH_3) groups to histone amino terminal tails results in a/an in gene expression. Removal of acetyl groups from histones results in a/an in gene expression.
3. Which of the following is not a good example of a housekeeping protein in eukaryotic cells? a)DNA polymerase b)histones c)RNA polymerase 4)hemoglobin Explanation: 4. Which of the following statements about histones is true? a. Histones activate transcription when bound to the promoter, b. Although RNA polymerase can access DNA packed around histones, the general transcription factors and transcriptional regulators cannot. c. Histone acetyltransferases affect transcription by adding acetyl groups to histones and altering chromatin structure to allow accessibility to...
Histone de-acetylases prevent further gene expression in which of the following ways? Restoring the charge attraction between histones and DNA Preventing transcription factor binding Lessening the charge attraction between histones and DNA Adding a chemical tag to the DNA that silences it
3. Persistence length of DNA and energy cost of bending DNA around histone proteins (a) DNA is stiff because it is a double helix. At room temperature in dilute solution the persistence length of DNA is found to be p-50 nm. Using this persistence length, find the bending spring constant of DNA (b) In chromosomes, DNA molecules are wrapped tightly around histones. Consider wrapping a DNA molecule around a full circle, estimate the energy cost of bending DNA around the...
Question 5
QUESTION 2 What is common between histone proteins and spermidine? Histones and Spermidine are negatively charged. Histones and spermidine help DNA attain a random coil conformation They both play a role in DNA packaging. Histone and spermidine are present only in bacteria. QUESTION 3 Which of the following is NOT is product of Kreb's cycle NAD+ ATP FADH2 CO2 QUESTION 4 The amino acid responsible for introducing kinks in DNA helical structure by intercalation is Phenylalanine Ethidium Bromide...
You are interested in the interactions of histone deacetylase
(HDAC) with nucleosomes. Using a DNA template that is end labelled
with 32P and has two nucleosomes already bound to it, you perform a
gel-shift experiment with HDAC and the chromatin from above. You
also assemble chromatin with nucleosomes that have been methylated
at a particular amino acid residue of Histone H4. The results are
below. Based on the data, (A) explain the autoradiogram below –
what are all the bands?...
ton is not an energy dependent process in (B)) Falls eukaryotes 43. Histone methylation is associated with Falls gene activation gene silencing Following histones are required during transcription (A) H2A and 2B (B) H3 (C) H4 (D) All of the above (E) H2AZ (c) induction (D) All of the above (E) None of the above 35. 4. DNA methylation silences gene expression AD True (B) Fall Leucine residues in lucine zipper proteins provides h ydrophobic interaction for dimerization (A) True...
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