Question

What should happen when you put the FGF8 beads on the left side? A. nodal will...

What should happen when you put the FGF8 beads on the left side?

A.

nodal will be expressed on the left side

B.

left-right asymmetries will be randomized

C.

both Pitx-2 and snail will be expressed on the left side

D.

left-right asymmetries will form normally

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Answer #1

Answer :- c). both Pitx-2 and snail will be expressed on the left side.

Visceral organ handling is conserved among vertebrates and is regulated by asymmetric signals transmitted by molecules like Shh, Nodal, and activin. The Pitx2 gene is expressed in the mesoderm of the left lateral layer, and subsequently in the mouse, chick and Xenopus embryos of the left heart and gut. Misexpression of Shh and Nodal induces expression of Pitx2 while inhibition of activin that signals bl.

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