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Carbonic acid present in the blood comes mainly from dissolved carbon dioxide (CO2). Dissolved carbon dioxide,...

Carbonic acid present in the blood comes mainly from dissolved carbon dioxide (CO2). Dissolved carbon dioxide, CO2(aq), reacts with water to produce H2CO3.

a) Write the equilibrium expression for this process.

b) The equilibrium constant for this reaction is the hydration constant for CO2, Kh = [H2CO3]/[CO2(aq)] = 3.0 x 10−3 . Combine this equation with the expression you derived in 1.a) for the equilibrium expressions for the first ionization (controlled by Ka1) and rearrange to obtain the apparent equilibrium constant: Kapp = [HCO3 − ][H+ ]/[CO2(aq)]. What constants is Kapp composed of? What is the value of Kapp and pKapp?

c) The concentration of dissolved CO2 in the blood is approximately 1.2 mM and the concentration of HCO3 − is approximately 25 mM. What is the pH in blood serum?

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