Draw the reaction for the hydrolysis of phosphatidylcholine (with 18:0 and 18:1 Δ9 as the acyl chains) in the presence of phospholipase C (PLC). (PLC cleaves at the third carbon on the glycerol backbone).
Draw the reaction for the hydrolysis of phosphatidylcholine (with 18:0 and 18:1 Δ9 as the acyl...
(Only answer 'B'). The more specific you are, the better!
Phospholipase A2 is an enzyme that cleaves the ester linkage on C-2 of glycerol of phospholipids. It has a variety of purposes in the cell, many of which are outlined in your book. Additionally, the venoms of several dangerous creatures also contain enzymes with phospholipase A2 activity. The eastern diamondback rattler and Indian cobra, for instance, kill more than 10% of their human victims. The breakdown product of phospholipids is...
3. (9 pts) Glycerophospholipids A. (6 pts) Draw the structure of phosphatidylcholine at pH 7. Assuming that different aliphatic side chains are attached to the backbone, circle all chiral centers. B. (1 pts) What is the net charge of this lipid? C. (1 pts) What are the bonds called that connect the aliphatic side chains to the backbone? D. (1 pts) What is the parent compound of glycerophospholipids?
Reference the following molecule: 1-stearoyl, 2-lenoleoyl(18:2Δ9,12) phosphatidylcholine. Q: Draw sphingomyelin with an N-palmitoyl substitution.
The venom of the Eastern diamondback rattler and the Indian cobra contains phospholipase A2, which catalyzes the hydrolysis of fatty acids at the C-2 position of glycerophospholipids. The phospholipid breakdown product of this reaction is lysolecithin (lecithin is phosphatidylcholine). At high concentrations, lysophospholipids act as detergents, dissolving the membranes of erythrocytes and lysing the cells. Extensive hemolysis may be life-threatening. Draw the lysolecithin that results when a phosphatidylcholine molecule is exposed to phospholipase A2. Represent any acyl groups as "R."...
Draw the following molecule: 1-steric, 2-lenoleoyl(18:2Δ9,12) phosphatidylcholine Draw platelet-activating factor Draw sphingomyelin with an N-palmitoyl substitution What is the physiological relevance of each lipid you have drawn above? Describe two similarities that all three lipids share.
Draw the structures of the complete hydrolysis products of the following compound: There is a scheme of a reaction, where a molecule, whose structure is CH3CH2CH2CHOCH3 with an -OCH2CH3 group attached to the fourth (from left to right) carbon atom, reacts with an H2O molecule in the presence of acid.
Draw the structures of the complete hydrolysis products of the following compound: There is a scheme of a reaction, where a molecule, whose structure is CH3CH2CH2CHOCH3 with an -OCH2CH3 group attached to the fourth (from left to right) carbon atom, reacts with an H2O molecule in the presence of acid.
Reference the following molecule: 1-stearoyl, 2-lenoleoyl(18:2Δ9,12) phosphatidylcholine. Q: draw the platelet-activating factor. Explain the physiological relevance of each lipid in the molecule.
Draw the product of the reaction.
Draw only the product derived from the acyl portion of the
carboxylic acid or acid derivative.
You do not have to consider stereochemistry.
Thank you!
C-CoC CHANH,
1) Draw the mechanism of the acyl substitution reactions shown below. Proton transfer steps are labeled where needed. a) Make an ester (8 pts) oi on b) Make an amide (10 pts) 6) Make an amis (10 pcs) c) Acid catalyzed hydrolysis (12 pts) H2SO4 H2O