Question

For each of the following questions, give the correct answer. However, don't just answer the question. For each answer choice, you have to provide at least a paragraph response on why that answer choice is correct or incorrect with relevant and outside information.

The symptoms of a certain inherited disorder in humans include male sterility. Which of the following is a reasonable hypothesis for the molecular basis of this disorder?

A. a defective enzyme in the mitochondria

B. defective dynein molecules in flagella

C. abnormal hydrolytic enzymes in the lysosomes

D. defective ribosome assembly in the nucleolus

Answer 1

locomotion is of utmost importance and thus can expect flagella, which would help in motility to play a key role.

A defective enzyme in mitochondria would possibly slow down the synthesis of ATP but will not affect the flagella directly.Actin molecules in cellular microfilaments will not influence the flagella as flagella are made of microtubules and not microfilaments..Lysozymes are of more importance in cells in immune system and their abnormal function would not cause defective sperm. T is the dnein molecules that act as molecular motors in flagellum movement that will affect this movement most directly. .

Lastly the ribosome assembly might harm overall protein synthesis and is not confined to the sperm.

However, defective dynein molecules in flagella would mean impaired movement of the flagella and hence defective sperm leading to infertility.

This can have important applications in treating fertility. Knowing this is important in treating infertility. A lack of this knowledge might cause incorrect treatment where the count of defective sperms could be increased to no effect.