Which of the following is required for commitment to muscle fate? A. sox2 B. runx1 C....
Which of the following is required for commitment to muscle fate?
| A. |
sox2 |
|
| B. |
runx1 |
|
| C. |
smad1 |
|
| D. |
myogenin |
Homework Answers
Answer - Myogenin is required for commitment fate muscle. Myogenin is a muscle-specific basic-helix-loop-helix (bHLH) transcription factor involved in the muscle development(myogenesis), repair of muscles and coordination muscles. Myogenin is a member of the MyoD family of transcription factors
SOX2 is incorrect because Sox2 helps in the maintenance of embryonic and neural stem cells but not in muscle development
RUNX1 is incorrect because it helps in the differentiation of hematopoietic stem cells into mature blood cells and in the development of the neurons but not in muscle development
SMAD is also incorrect because SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signalling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses but do not help in muscle development
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Which of the following is required for commitment to muscle
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