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How can bacteria be resistant against antibiotics discuss at least 3 mechanism

How can bacteria be resistant against antibiotics discuss at least 3 mechanism

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Ans:- 3 mechanisms of bacterial resistance to antibiotics are as follows:-

1. Decrease permeability,

2. Activation of drug pumps,

3. Change in drug binding sites.

1. Decrease permeability :- In this mechanism the  receptor that transports the drug is altered so the drug cannot enter the cell and bacteria becames resistant for the antibiotics.

2. Activation of drug pumps:- In this mechanism specialised membrane proteins are activated and continually pump the drug out of the cell and bacteria became resistant.

3. Change the drug binding sites:- In this mechanism binding site on target ribosome is altered so drug has no effect on bacteria.

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