What happens if you run the TLC plate in 100% acetone instead of 30:70 Acetone: Hexane?
Below is a hypothetical TLC of 3 compounds run in 10% acetone/90% hexane. What would the TLC look like if it had been run in 20% acetone/80% hexane instead? 10% acetone 90% hexane ОА OB oc o We need more information such as whether the 3 compounds are polar or nonpolar.
A TLC plate was run in 1:1 ethyl acetate and hexane, but when developed the plate only showed baseline spots. What change could be made to get the spot(s) to move further up the plate? -Spot a new plate and run again in the same solvent system -Spot a new plate and run in neat hexane -Spot a new plate and run in 1:2 ethyl acetate/hexane -Spot a new plate and run in 2:1 ethyl acetate/hexane
The solvent: 70/30 (hexane/ethyl acetate)
Compounds: Hexane, 70/30 (hexane/ethyl acetate), and 95/5
CH2Cl2/CH3OH
I r ry Pus uey.UUT TU eu puru The solvent for TLC works well as separating these 3 compounds. Rationalize why it was chosen, discussing polarity of solvent and the 3 ferrocenes.
TLC Consider the following silica gel TLC plate of compounds A, B, and developed in hexanes: solvent front 0 D origin A B C 22. Determine the Ry values of compounds A, B, and Crun on a silica gel TLC plate using hexanes as the solvent. 23. Which compound, A, B, or C, is the most polar? 24. What would you expect to happen to the Ry values if you used acetone instead of hexanes as the eluting solvent? 25.TLC...
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You have run a TLC (on a silica plate), your sample contains a very polar compound A, a non-polar compound B, and a moderately polar compound C. What order, from top to bottom, will they appear on the TLC plate? (a) ABC (b) CBA (c) ACB (d) BCA (e) BAC
in 10:1 Hexane: 8: Use the image below to answer the following questions. The TLC plate was run gityl Acetate. (4 points А.suong ial 8 -Starting Material and Reaction Product A) Calculate the Rf value for the starting material. (1 point) B) Calculate the Rf value for the product.(1 points) C) Is the product or the starting material more non-polar? (1 point) D) Is the reaction complete? (1 point) Question 9: Label the following peaks a-e on the H-NMR spectra...
Possible Quiz Questions 1 What two methods of visualizing spots on a TLC plate will you use in this Give two reasons why would you predict that the elution solvents (hexanes or acetate) would not be visible under UV visualization? week's lab? ethyl 2. Define R 3. Calculate the R of the spot on the following TLC plate. 4. Which compound in each pair is predicted to have the higher Ri? a. CH3CH2CH2CH2OH and CH3CH2CH2CH28r b. CH3CH2CH2CH2OH and CH3CH2CH2CH2CH2CH2CH3 c....
Common solvents used in TLC analysis are hexane and ethyl acetate, the latter being more polar. A TLC has been performed on a mixture of two compounds. The solvent ran for 3 cm(plate length is 6cm) with 5% ethyl acetate in hexane. The two spots were not resolved, meaning they showed up too close to each other. What can you suggest to possible improve the results of the separation?
Explain how you used TLC analysis to identify each product obtained from the dihydroxylation reactions. Explain why 100% ethyl acetate was used to develop your TLC plate (and not 100% hexane or a mixture of hexane/ethyl acetate)?
2. What are the phases involved in TLC? 3. What is coated on the TLC plate? 4. What is the purpose of lining the wall of the TLC chamber with paper? 5. Why is it important to use a small amount of the mobile phase? 6. Why should you remove the TLC plate before the mobile phase reaches the top? 7. What type of compounds are visible with UV light? 8. With a polar stationary phase and non-polar mobile phase,...