The standard free energy change of the glycolytic pathway to pyruvate is -79.9 kJ/mol, while the standard free energy change associated with gluconeogenesis from pyruvate is -42.7 kJ/mol. What would the standard free energy change be for a direct reversal of the glycolytic pathway.
Ans: +79.9 kJ/mol
we can able to determine the direction of reaction by measuring the free energy or G because of our biological system functions at constant temperature and pressure.
The equation for free energy change is
ΔG = Gproducts - Greactants
where Δ is a difference and G is a free energy
As per a scientist Gibbs, at constant temperature and pressure, our biological systems change to minimize free energy.
So, If ΔG is negative for chemical reaction indicates forward reaction
If ΔG is positive, which indicates reverse reaction and if the ΔG is zero, which indicates both forward and reverse reaction at equal rates or the reaction is at equilibrium.
So, If the standard free energy change of the glycolytic pathway to pyruvate is -79.9 kJ/mol then the standard free energy change for a direct reversal of the glycolytic pathway is +79.9 kJ/mol
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