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. CheB is a methylesterase that demethylates the receptor. The protein contains two domains: the N-terminal...

. CheB is a methylesterase that demethylates the receptor. The protein contains two domains: the N-terminal domain is the regulatory domain, and the C-terminal domain is the catalytic domain. CheB is activated by phosphorylation, which causes a conformational change that exposes the active site in the catalytic domain.

a) What is the difference between a two-domain protein and a two-subunit protein?

b) What would you expect to be the phenotype of a mutant that lacked the N-terminal domain of CheB?

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Answer #1

a. Protein subdomain is a part of protein subprotein. Two domain protein means protein (single polypeptide) with a single protein with two domains whereas protein subunit consist of one or more polypeptide chain.

b. The protein that lack N terminal of cheB protein, which do not have regulatory sequence, will not able to express because of the absence of structural domain.

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