How does a GTP cap prevent a microtubule from falling apart, and how does a microtubule lose its GTP cap?
If the rate of adding GTP-heterodimers to a microtubule is greater than the rate of GTP hydrolysis, then will the microtubule continue growing or fall apart? Explain your answere.
Assume that in a normal cell the average length of microtubule reaches before falling apart is 8 micrometers. Imagine a cell with mutant B-tubulin that catalyzes hydrolysis at a rate slower than B-tubulin of the normal cell. Will the average length of microtubules, in the mutant cell, be greater or less than the average length in the normal cell? Explain your answer.
How does a GTP cap prevent a microtubule from falling apart, and how does a microtubule...
Consider a mutation in tubulin that alters how tubulin changes its conformation after GTP hydrolysis. More specifically, the mutation makes tubulin "stiffer" after GTP hydrolysis, such that the tubulin does not transition as quickly between the straight and curved conformations. How would microtubule dynamics be affected by this mutation? Select all that apply. Question 5 options: a) Microtubules will grow faster (the net growth rate increases). b) Microtubules will shrink more slowly after a catastrophe (the "post-catastrophe shrinkage rate" is...
1) Comparisons of microtubule behavior between species point to
differences that raise questions about the biological importance of
dynamic instability. Notothenioid fish, for example, which live in
the Southern Ocean at a constant temperature of –1.8°C, have
remarkably stable microtubules compared with warm-blooded
vertebrates such as the cow. This is an essential modification for
notothenioid fish because normal microtubules disassemble
completely into αβ-tubulin dimers at 0°C. Measurements on
individual microtubules in solutions of pure tubulin show that
notothenioid fish microtubules...
Comparisons of microtubule
behavior between species point to differences that raise questions
about the biological importance of dynamic instability.
Notothenioid fish, for example, which live in the Southern Ocean at
a constant temperature of –1.8°C, have remarkably stable
microtubules compared with warm-blooded vertebrates such as the
cow. This is an essential modification for notothenioid fish
because normal microtubules disassemble completely into αβ-tubulin
dimers at 0°C. Measurements on individual microtubules in solutions
of pure tubulin show that notothenioid fish microtubules grow...
Question 1 of 8 2.0 Points Which of the following statements about the cytoskeleton is false? A. The cytoskeleton is made up of three types of protein filaments. B. The cytoskeleton controls the location of organelles in eukaryotic cells. C. Covalent bonds between protein monomers hold together cytoskeletal filaments. D. The cytoskeleton of a cell can change in response to the environment. Reset Selection Question 2 of 8 2.0 Points Which of the following statements about the function of the...