Which of the following would most likely be true in the presence of an uncoupling agent?...
Which of the following would most likely be true in the presence of an uncoupling agent?
A) Electron transport at the inner mitochondrial membrane would cease.
B) The energy from the proton-motive force would likely be dissipated as heat rather than in producing ATP from ADP.
C) H+ ions would flow through the inner membrane into the intermembrane space.
D) There would be an increase in biosynthesis.
Homework Answers
Answer=
Most likely true in the presence of an uncoupling agent is
B) The energy from the proton-motive force would likely be dissipated as heat rather than in producing ATP from ADP.
Explanation = An uncoupling agent is a mitochondrial inner membrane protein that is a regulated protein channel or transporter.
Uncouplers of oxidative phosphorylation in mitochondria inhibit the coupling between the electron transport and phosphorylation reactions and thus inhibit ATP synthesis.
- Uncoupling agent is capable of dissipating the proton gradient generated by NADH-powered pumping of protons from the mitochondrial matrix to the mitochondrial intermembrane space.
- The energy lost in dissipating the proton gradient is not used to do biochemical work instead it heat is generated.
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