Question

5) An exceedingly rare genetic condition known as congenital generalized hypertrichosis leads to excessive facial and body hair.

a) Suppose you are a genetic counselor whose client, a woman, has this condition. In the course of your interview, you learn that her sister and her father have similar symptoms, but neither her mother nor any of her four brothers has the disease. Draw a pedigree for this family.

b) Based on the available information, decide whether this disease is dominant or recessive and whether it is sex-linked or autosomal. Give specific evidence to support your conclusions.

c) Assign symbols to the alleles and assign genotypes to each of the individuals in your pedigree.

d) If your client marries a man with no family history of the disease, what is the probability that she will have an affected child?

(c & d are most important questions to answer)

Answer 1

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