1. What feedback loop functions in the shoot apical meristem in order to regulate meristem size?...
1. What feedback loop functions in the shoot apical meristem in order to regulate meristem size?
2. In this system, what is the mobile signal (ligand), and what is the receptor protein?
3. In this system, what is the name of the protein whose expression acts as a pacemaker, controlling the levels of cell division within the meristem and thus the size of the meristem?
Homework Answers
Stem cells of meristematic region are maintained in an
undifferentiated state by the signals of organising centre. There
is a feedback signalling group present between the stem cells and
organising centre, which balances stem cell renewal versus
differentiation, which allows the plant to maintain the
organization of the shoot meristem.
The presumed stem cell region is characterized by the expression of
the CLAVATA3 (CLV3) gene, CLV3 gene is used as an operational stem
cell marker for the shoot meristem.
The CLV3 gene encodes a small peptide. This peptide is secreted
into the extracellular space. This peptide acts as a ligand for the
CLV1 receptor-like kinase in the extracellular space. CLV1
receptor-like kinase is expressed throughout most of the shoot
meristem.
SHEPHERD is an HSP90- is the protein that acts as the pacemaker. This is required for CLV signaling.
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