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. Design a Live attenuated vaccine to limit the pathogenicity of Mycobacterium leprae

. Design a Live attenuated vaccine to limit the pathogenicity of Mycobacterium leprae

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The only licensed TB vaccine, bacillus Calmette Guérin (BCG), is a live attenuated vaccine derived from Mycobacterium bovis.In addition, BCG vaccination offers little to no protection against pulmonary TB, cannot eliminate latent M. tuberculosis, and is ineffective at preventing subsequent TB.Multidrug therapy uses combinations of antibiotics that kill M.leprae including: dapsone, rifampin, clofazamine, fluoroquinolones, azithromycin, and minocycline. Antibiotics must be taken regularly until treatment is complete due to the fact M. leprae has the ability to grow back.A preventive measure of M. leprae is to avoid close contact with infectious people who are untreated

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