If protein is mutated and causes disease, what mechanism of drug can treat this disease?
If protein is mutated and causes disease, what mechanism of drug can treat this disease?
Inactivation of protein P causes a disease D. The mRNA from the affected individuals in the same family had a deletion of 113 nucleotides. The comparison of the gene sequence between the affected and healthy individuals identified one nucleotide substitution. A) What could be the molecular mechanism that cause the deletion of 113 nucleotides in the mRNA? B) What can happen to the protein P as a result of this deletion? C) What can you conclude about the molecular basis...
12. Answer a few questions about sickle cel What protein is mutated in a person with sickle cell anemia? With respect to the protein, What TYPE of mutation causes sickle cell anemia? What specific amino acid(s) have changed in the protein, and how specifically does the DNA code for the mutant gene differ from the "normal" gene? How does this mutation in one protein cause the disease sickle-cell anemia? Which person in the pictures at the beginning of this section...
when dealing with Crohn's Disease 1) What are the mutated genes that are associated with this disease and explain each one of them? 2) In detail, explain the genetics in this disease 3) Explain how does Crohn's disease work and the mechanism behind it? Thank You!!!
Osteogenesis Imperfecta is a disease that causes fragile bones. Scientists introduced a mutated form of type 1 collagen into mice and found that 70% of the mice exhibited symptoms similar to humans; however, 30% of the mice with the same genotype appeared completely normal. This is an example of A. environmental influence B. variable expression C. codominance D.epistasis E. incomplete penetrance F. complementation G. incomplete dominance
16. When a Cys residue in a protein is mutated to Asp, the protein loses its function. Which is the least likely explanation? A. The protein is part of ESCRT-O and therefore requires a disulfide bond at the Cys for stability. B. The protein is a Rab and the Cys is in a Caax prenylation motif. C. The protein is an E2 ubiquitin conjugating enzyme and the Cys is the attachment site for ubiquitin. D. The Cys is part of...
on this topic anticoagulants, discuss the drug in detail, mechanism of action, conditions we treat with your category of drug, name a few drugs found within your category, side effects of each drug, contradiction or precautions for using the drug, and interactions. please include a few things you would teach your patient who has been prescribed a medication from anticoagulants.
How to treat Type I hypersensitivity? Please describe the mechanism of action behind the drug(s)
L-Dopa is a drug used to treat Parkinson's disease. (Write your molecular formula m the following format: C_wH_xS_yO_z) a. What is the molecular formula of L-dopa? b. What is the formula weight of L-dopa? c. What is the molar mass of L-dopa?
Drug manufactures of Drug X, which was released on the market 5 years ago to treat Crohn’s disease, have noticed that many individuals treated with the drug have developed drug-induced lupus. A cohort study was conducted for post-marketing surveillance. It has documented that 9 individuals have developed drug-induced lupus over the course of the past 5 years. If 2 individuals developed the disease at the 1-year mark, 3 developed the disease at the 2-year mark, 1 developed the disease at...