HomeworkLib
Question

The protein sequence of myoglobin has aspartate (D) in a certain position, whereas the α chain...

The protein sequence of myoglobin has aspartate (D) in a certain position, whereas the α chain of hemoglobin has glutamate (E) in the same position.
How would this difference be scored in a Blosum‑62 matrix? choose the correct answer

a) It would be given a negative substitution score.

b) It would result in a single‑residue gap penalty.

c) It would be given a positive substitution score.

d) It would be scored as an identity.

e) It would have no effect on the score.

science   biology   
0 0
Add a comment Improve this question Transcribed image text
Next > < Previous
Sort answers by oldest

Homework Answers

Answer #1

Answer

Option C is correct i.e " It would be given a positive substitution score ".

Explanation

As both the amino acids Aspartate (D) and Glutamate (E) are negatively charged and both amino acids imparts negative charge to protein. Hence, it does not effect the functionality of protein that's why positive score will be given.

0 0
Add a comment
Know the answer?
Add Answer to:
The protein sequence of myoglobin has aspartate (D) in a certain position, whereas the α chain...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions

  • jnment Score: Resources Give Up? Hint Check Answer estion of 10 > Consider the two sequence...

    jnment Score: Resources Give Up? Hint Check Answer estion of 10 > Consider the two sequence alignments. Alignment 1. A-SNLFDIRLIG GSNDFYEVKIMD Alignment 2 ASNLFDIRLI-G GSNDFYEVKIMD Calculate the alignment scores of each sequence alignment using identity-based scoring and the Blosum 62 substitution matrix. The identity-based scores should incorporate a gap penalty. In this case, the Blum-62 substitution matrit does not impose a gap penalty Blosum-62 Substitution Matrix Ala Arg Asn Asp Cys Gin Glu Gly His Ile Leu Lys Met Phe...

  • Using the following peptide, answer the following questions: HWESPGHAKCNKL. A.) This peptide has the following pKa...

    Using the following peptide, answer the following questions: HWESPGHAKCNKL. A.) This peptide has the following pKa values associated with it: 2.1, 4.3, 6.0, 8.1, 9.3 & 10.7. What is the pI for this peptide? B.) What would be the overall charge on this peptide at: (i) pH 12? (ii) pH 7? C.) If this protein has the following modifications: one K side chain which is acetylated and the S side chain is phosphorylated. What would be the approximate pI for...

  • Hagrid has purified a protein from unicom sweat and called UNI-1. He has then doned the...

    Hagrid has purified a protein from unicom sweat and called UNI-1. He has then doned the Unit gone and inserted in rat zygotes (by microinjection) a recombinant construct containing the Uni-1 coding sequence its entire 5 UTR region, covering both the minimal promoter and a series of cutative regulatory als elements. The mutantrats develop glorious, luminous hair. Hagrid has also discovered that the UNI-1 protein binds very tightly to DNA and hypothesizes it is a transcription factor that regulates proliferation...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT