Question

Choose the repair mechanism that is best associated with the statement. Some statements may have more than one answer.

a. nucleotide excision repair

b. mismatch repair

c. translesion synthesis

d. recombinational repair

e. base excision repair

_____ 1. Uses an enzyme called the DNA-N-glycosylases.

_____ 2. Utilizes a group of proteins called Mut.

_____ 3. The disease Xeroderma pigmentosum is caused by a defect in this system.

_____ 4. This is associated with the SOS response in bacteria.

_____ 5. Removes a short segment of DNA around the damaged bases.

_____ 6. Removes a single abnormal base from the DNA.

_____ 7. This may be used to repair an unreplicated gap in the DNA.

_____ 8. Identifies the parental strand by methylation patterns, then uses it as a

template for repairing the damage to the unmethylated strand.

_____ 9. Abnormal nucleotides are recognized by AP-endonuclease.

_____ 10. Uses the Uvr proteins in the response

Answer 1

1.e.base excision repair- Uses an enzyme called the DNA-N-glycosylases.

2.b.mismatch repair- Utilizes a group of proteins called Mut.

3.a.nucleotide excision repair- The disease Xeroderma pigmentosum is caused by a defect in this system.

4.a.nucleotide excision repair-C.translesion synthesis-

This is associated with the SOS response in bacteria

5.a.nucleotide excision repair-Removes a short segment of DNA around the damaged bases.

6.e.base excision repair-Removes a single abnormal base from the DNA.

7.recombination repair -This may be used to repair an unreplicated gap in the DNA.

8.b.mismatch repair -Identifies the parental strand by methylation patterns, then uses it as a template for repairing the damage to the unmethylated strand.

9.e.base excision repair-a.nucleotide excision repair -Abnormal nucleotides are recognized by AP-endonuclease.

10.a.nucleotide excision repair- Uses the Uvr proteins in the response