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To help you synthesize all you’ve learned to this point, use Le Chatelier’s principle to hypothesize...

To help you synthesize all you’ve learned to this point, use Le Chatelier’s principle to hypothesize why the formation of H2CO3 is occurring in the osteoclast.

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Le Chatelier’s principle states that if a system at equilibrium is exposed to stress the system will shift to relieve that stress. When stress is created due to absorption of calcium from bones, this activates the osteoblast species which starts producing osteoid, the organic component of bone.

The osteoclast releases the hydrogen ions through the action of anionic anhydrase (H2O + CO2 → HCO3 + H+) acidifying and helping dissolution of mineralized bone matrix to Ca2+ ,H3PO4, H2CO3. This minaralized matrix is absorbed by osteoclast.

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