Explain why patients with a UTI caused by Proteus mirabilis would have a higher than normal...
Explain why patients with a UTI caused by Proteus mirabilis would have a higher than normal urine pH.
Homework Answers
Normal pH of urine is usually in the range of 4.5-8.
Low pH of urine means that urine is acidic and high pH of urine means it is alkaline.
Alkaline urine in UTI' s may be due to break down of urea into ammonia and other alkaline products.
Proteus mirabilis is a gram negative bacilli that swarms. It also has the ability to convert urea into ammonia. In the case of Proteus, the urease enzyme is very potent often leading to urosepsis and other complications as both the rapid movement and multiplication of Proteus and the high activity of of urease enzyme leads to crystallization of ammonia and calcium salts leading to blockages of the UT. Thus urine in patients suffering from UTI caused by this organism has a high pH than normal.
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