Question

answer the following questions for the gene listed below:

Tail Assembly Chaperone

1) Function (what process is the gene a part of? Why does the phage need this gene)

2) Where is it usually found in Mycobacterial Phages? (Begining? middle?, end? of genomes)

3) Is there a predictive synteny pattern associated with the gene? (What is upstream or downstream?)

Answer 1

1. The function of Tail Assembly Chaperons is to morphogenesis of long-tail phages. It is found in the virus, the gene works on programmed translational frameshift, giving rise to two chaperons which are found in an overlapping sequence. This allows the organism to develop into a particular shape. It helps in spiral structure formation which is associated with protein causing evolution. The phage needs the gene for folding and oligomerization of long and short phage tail fibers.

2. These chaperones are found in the entire tail region which includes the middle and end of the genomes.

3. The Tail assembly chaperons are in predictive synteny pattern associated with lambdoid like phages. The sequence associated with gpGT production.

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