Question

Why does p53 play a critical role in the cell cycle checkpoint maintenance ?

1. p53 is not critical for the cell cycle checkpoint maintenance

2. The cells will stop dividing and will stay in G0 phase if p53 was mutated

3.The cell will ignore DNA damage and allow the cell to enter the next cell cycle phase if p53 was mutated.

4.The cells will stop division and go through apoptosis if p53 was mutated

Answer 1

3rd one is correct answer because p53 is responsible for damage repair of DNA and if this gene is not present ,cell will enter in next phase