Question

In a population of red-spotted newts, gamete genotypes at two loci are sampled. 51% are AB, 29% are Ab, 9% are aB and 11% are ab.

1). Estimate the allele frequencies at each locus.

2). Calculate the expected frequencies of gametes at linkage equilibrium and the absolute value of D (D is disequilibrium coefficient)

Suppose the recombination rate between the A and B loci is 0.2. What is the expected disequilibrium in the next generation?

Answer 1

1)

In this case, the allele frequencies will we the sum of the frequencies of those gametes that contain the allele.

2)

The frequency of the gametes in equilibrium it's the multiplication of the allele frequencies of each allele for locus A and locus B.

r: recombination rate