Question

One molecule of palmitate can be synthesized from 4.5 molecules of glucose. Which one of the following is nearest to the number of high energy phosphate bonds used (-) or generated (+) in the synthesis of palmitate from glucose? (Assume the Aspartate Malate shuttle)

a. +20

b. +10

c. 0

d. -10

e. -20

Answer 1

-10 is the answer from 1 molecule of glucose 2 ATP is produced while making glucose and 1.5 ATP utilised for making 0.25 molecule palmitate from acetyl CoA