Question

Activated T helper cells are excluded from what process?

A. differentiation into TH1 cells

B. the differentiation into TH2 cells

C. the differentiation into memory TC cells

D. recognition of MHC with antigenic peptide on macrophages

Answer 1

Answer is: C. the differentiation into memory TC cells

Explanation:

The helper T cells (TH cells) receives signals for activation and becomes Th0 cells also known as T helper 0 cell. It secretes IL-2, IL-4 and interferon gamma (IFN-γ).

The Th0 cells then differentiates into Th1 or Th2 cells. IFN-γ give signals for Th1 cell production and IL-4 give signals for Th2 cell production.

Helper T cells do not directly kill infected cells directly, they activate cytotoxic T cells and macrophages that kills infected cells and also stimulates B cells to secrete antibodies.

TH1 cells boost macrophages to digest bacteria. TH2 cells activate B cells to produce antibodies.

Antigen-presenting cell is defined as presentation of antigens which are bound to MHC molecules on the surface of a cell. An antigen presentation activates helper T cell to differentiate into TH1 or TH2 effector helper cell.