Question

1. What is the resulting new trait for this mutation? What are the resulting symptoms in people with the HbS hemoglobin protein?

Answer 1

People having Heterozygous HbS allele are carrier for sickle cell anaemia and are less asymptomatic.

While people homozygous for HbS allele show the symptoms like-

-breath shortness( due to lack of oxygen carrying capacity of hemoglobin)

- inflamed fingures and toes( hemoglobin inability to reach at the tip)

- pain in chest & joints.

- dizziness, fatigue and pale skin.etc.

This mutation in HbS gene is inherited via-​​​Autosomal recessive trait.