Question

18) Which of the following statements correctly describe the role of transcription factors in the initiation of transcription in eukaryotes?

A) Some transcription factors must bind to the promoter before RNA polymerase II can bind.

B) Some transcription factors must bind to the promoter proximal element to sure significant levels of mRNA production

C) Some transcription factors can bind to enhancer elements thousands of base pairs away from the gene

D) Some transcription factors can bind to silencer elements that might be located thousands of base pairs away from a gene to reduce mRNA transcription

E) All of the above

Answer 1

Please find the answer below:

18) Which of the following statements correctly describe the role of transcription factors in the initiation of transcription in eukaryotes?

Answer: A) Some transcription factors must bind to the promoter before RNA polymerase II can bind.

Explanation: The initiation of transcription cannot be done by the RNA polymerase itself. The transcription factors have to bind to the promoter and then recruit the RNA polymerase, in order to establish the transcription.