What types of reactivity are you going to use when synthesizing NMP- the prodrug for fluoxetine?
What types of reactivity are you going to use when synthesizing NMP- the prodrug for fluoxetine?
Homework Answers
There are many procedures available to synthesize the prodrug NMP. Below are the reactivity types discussed as per the paper "Daniel M. Perrine, Nathan R. Sabanayagam, and Kristy J. Reynolds", "Journal of Chemical Education 1998 75 (10), 1266".
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What types of reactivity are you going to use when synthesizing NMP- the prodrug for fluoxetine?
Propose another way of synthesizing NMP from the amino ketone hydrochloride salt starting materia...
Propose another way of synthesizing NMP from the amino ketone
hydrochloride salt starting material you used.
Part A: Synthesis of (t)-N,N-dimethyl-3-phenyl-3-(4- trifluoromethylphenoxy)propanamine 1. To the 250-mL round-bottom flask (RBF) containing (t)-3-(dimethylamino)-1-phenylpropanol (product from Lab 6) and a magnetic stir bar, add 4 mL of 4- chlorobenzotrifluoride and 30 mL of dimethylacetamide (DMA) 2. With stirring, add to this mixture 30 mL of 1.0 M potassium tert-butoxide (caustic alkali!) in tert-butyl alcohol using a syringe 3. Using a simple distillation apparatus,...
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RC is a 35 year old woman, who is prescribed fluoxetine 20 mg in the evening for depression. RC reports troubles sleeping an gastrointestinal upset. RC states that she does not think the fluoxetine is helping. She states that she has heard about complementary and alternative therapies that may be taken for depression. She has also heard that fluoxetine can be taken weekly instead of daily. Using this scenario, thoroughly answer the following questions in your own words. Answers are...
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What types of systems are good candidates, from a networlk perspective, for going behind NAT/PAT devices? What types of systems are good candidates, from a networlk perspective, for going be...
What types of systems are good candidates, from a networlk perspective, for going behind NAT/PAT devices?
What types of systems are good candidates, from a networlk perspective, for going behind NAT/PAT devices?
Propose another way of synthesizing NMP from the amino ketone
hydrochloride salt starting material you used.
Part A: Synthesis of (t)-N,N-dimethyl-3-phenyl-3-(4- trifluoromethylphenoxy)propanamine 1. To the 250-mL round-bottom flask (RBF) containing (t)-3-(dimethylamino)-1-phenylpropanol (product from Lab 6) and a magnetic stir bar, add 4 mL of 4- chlorobenzotrifluoride and 30 mL of dimethylacetamide (DMA) 2. With stirring, add to this mixture 30 mL of 1.0 M potassium tert-butoxide (caustic alkali!) in tert-butyl alcohol using a syringe 3. Using a simple distillation apparatus,...
1. If you were going to make life preservers, which types of plastic would you use? Why? 2. You are going into a small business to manufacture handles for a barbeque. What properties are important for choosing a plastic to use manufacture BBQ handles?
RC is a 35 year old woman, who is prescribed fluoxetine 20 mg in the evening for depression. RC reports troubles sleeping an gastrointestinal upset. RC states that she does not think the fluoxetine is helping. She states that she has heard about complementary and alternative therapies that may be taken for depression. She has also heard that fluoxetine can be taken weekly instead of daily. Using this scenario, thoroughly answer the following questions in your own words. Answers are...
SYNT 451: Synthesizing Alum name Pre-Laboratory Ass 1. (1) What precautions should you take when you 3. measure 4M H,SO, and add it to the filtrate in Step 10? (2) What precautions should you take when you wash the synthesized alum with ethanol in Step 24? NO
CRITICAL THINKING CASE STUDY a 37-vear-old woman, is receiving fluoxetine 20 mg in the ning for depression. ST complains of insomnia and GI upset 1. What could you suggest to ST to help her avoid insomnia? Explain your answer. 2. How might ST avoid GI upset when taking fluoxetine? What food should be avoided? ST states that she does not think the fluoxetine is helping. She states that she has heard about complementary and alternative therapies that may be taken...
ST, a 37-year-old woman, is receiving fluoxetine 20 mg in the evening for depression. ST complains of insomnia and GI upset. 1. What could you suggest to ST to help her avoid insomnia? Explain your answer. 2. How might ST avoid GI upset when taking fluoxetine? What food should be avoided? ST states that she does not think the fluoxetine is helping. She states that she has heard about complementary and alternative therapies that may be taken for depression. She...
You are giving a person fluoxetine (Prozac). You should Select one: a. Remind the person to use caution when performing tasks that require alertness b. Measure the blood glucose frequentlyX c. Give the drug at bedtime d. Give the drug on an empty stomach 6 Before giving carbamazepine (Tegretol), you Select one out of a. Give good oral hygiene b. Measure weight c. Measure blood glucose X question d. Give the person food MacBook Air FIO 4 F1 4F12 5...
What types of systems are good candidates, from a networlk perspective, for going behind NAT/PAT devices?
What types of systems are good candidates, from a networlk perspective, for going behind NAT/PAT devices?
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