Question

3. You are determining the mode of action of a number of blood pressure modifying drugs. Based on the observations below, theorize how the following compounds prevent a homeostatic balance to blood pressure. e appropriate pathway on the next page, answer the following: When you exercise ows on your diagram to explain what is happening to your body to maintain a proper please explain and/or use arro MAP, assuming the appropriate changes in cardiac output when B) Your subject started walking on the treadmill and vou observed the appropri MAP rémained constant. You stabilized the treadmill at a constant 3 miles per hour to maint at a stable but elevated level. Your subject was injected with the drug TTRSAfter he was inje noticed that his MAP staned to go up steadily. As it was going up you n iate increase in cardiac output and his oing up you noticed the following: 1) his TPR did not, clevated but stablc levab (pre any as you can) and explain the actions of TTR#5 on this SPECIFIC njection Jevels). Please identi patient. (BE SPECIFIC AND DETAILED DOWN TO TIE MOLECULAR/ION LEVEL)

Answer 1

1. Blood pressure increased during excercising but MAP stays same.

Maintaining steady functions using baroreceptor reflexes

The stretching of arterial walls, veins and the heart

B.P get increased send a signal to the brain telling to relax the walls

Restoration of B.P&MAP in healthy persons.

2.Transthyret (TTR or TBPA) is a carrier protein in serum and CSF(cerebrospinal fluid) carries T4, Retinol binding protein. Choroid plexus secrete TTR into CSF. During excercising on threadmill, Heart beat faster to pump blood faster to muscles. Heart rate increases to transport O2 efficiently to muscles. So mean arterial pressure (MAP) will start increasing & the cardiac output. Brain loves excercise. The increased flow rate, O2, MAP will make alert, focused and awake. TTR works by releasing hormones into the CSF.