Question

H2O COH + RNH2 H+ or O HO- COH on on КОН N-H + R-X N-R Ο RNH2 aq. H2NNH2 ΝΗ Why can this reaction not be used to form 2 or 3 amines? Draw a reasonable mechanism for the hydrolysis (acidic or basic) and the Ing- Manske procedure.

Answer 1

ao ou 30 to foum the Reauten Used (annot be amines 50 SnNucleophite Potassiom Pthalamide 15 a ahimauy with 5Na Reauten esiy Happens Halides N-H KOH NK N-R O O beundauy oe Teiauy aye aides giuing us But in lase Etiminaien Reautien am also Ocur Not 50 Thats alkene H R-UH=UH-H3 -X R- CH NIC O auane CH3 joumaten

Mechanismo 8asic OH OH N-R N-R Ө H N-R NH-R он NH-R OM NH R HAN-R Produt

Proudwu Ing manske NHa ONH H NH2-NH2 N R N-R ethamo Proton Transox HN-NH2 NH R NH NH R. Pro ton NH Trans NH wmNHtoNH R 1 R. NH NH + R-NH2