
3.) Suggest two separate alcohol and alkyl halide combinations that could be used to produce the following ethers. Whic...
(5) Ethers can be synthesized using an alkoxide and alkyl halide. Provide two possible routes using an alkoxide and an alkyl halide to synthesize t-butylethylether, below . Label the route that is better and briefly explain why.
3. Beginning with an alcohol and an alkyl halide, draw two different routes to each of the following ethers using a Williamson ether synthesis (Smith 9.6). Indicate the preferred route (if there is one). Predict the products of dehydration (elimination) of the following alcohol. Read Smith 9.8A. Predict which product will be the major product. H.SO 2-pentanol Write a mechanism for the dehydration reaction (steps showing the flow of electrons with curved arrows). Read Smith 9.8B & 9.9. 2-methylcyclopentanol
2Beginning with an alcohol and an alkyl halide, draw two different routes to each of the following ethers using Williamson ether symthesis (Smith 9.6 Indicate the preferred route (if there is one), 8.
Using retro synthesis what alkyl halide and ketone were used to produce 3-ethyl-3-hexanol. The two starting materials cannot be 1-bromopropane and 3-pentanone. Calculate the percent yield of the final product which weighed 0.16g. The starting weight of Magnesium was 0.612g and starting weight of Ammonium Chloride was 0.6012g.
3. An alkyl halide is reacted with sodium iodide and sodium chloride in separate test tubes. The rate was the same in both experiments. Is this an Syl or an SN2 reaction? How would you know? 4. Why is sodium iodide used as a solution in acetone in these experiments instead of a solution in water? 5. Will the reaction below be Spl or Sn2? Show the mechanism.
Draw the structure of an alkyl halide that could be used in an E2 reaction to give the following alkene as the only alkene product:
Draw the structure of an alkyl halide that could be used in an
E2 reaction to give the following alkene as the only alkene
product:
Design syntheses to produce the following compounds starting
withany alkyl halide with 3 or fewer carbons and butadiene. You may
useany any inorganic reagents necessary. Note that once a compound
hasbeen synthesized in one process it can be used in a different
process ifyou reference where it was first made.
2 Rob page 6 Part B: 3 1. Classify the following cation, alkyl halide, and alcohol as either primary (1"), secondary (2) or tertiary (3) HO 2. Write the major product(s) A, B and C for the following transformations: RUBH NaOH, HO2 С Br2 NaOH ( excess) B А
Draw the structure of an alkyl halide that could be used in an E2 reaction to give the following alkene as the only alkene product. Hint: Look closely at the wording. ONLY alkene product - means only one product is formed СHз KО-Bu Check Answer Next Previous Exit