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Below are bases used in nucleic acids. (a) why are they called bases-what allows them to act as a base? (b) the two strands o

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(a) The lone pairs of electrons on Nitrogen atoms in the molecules can be donated to Lewis acids which make the molecules suitable Lewis bases.

(b) H- bond is the bonding interaction between an electronegative element in a molecule ( Like O, N, S or halogen) and a H atom attached to an electrinegative element in the same or different molecule.

(c) The drug should have potential to break the covalent bond between two DNA strands. So, the drug should be a strong nucleophile that attachs to a DNA strand breaking the covalent bond between the strands.

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