Question

Construct a three-step synthesis of 2-methyl-2-butanol from 3-methyl-2-butanol by dragging the appropriate formulas into the bins....

Construct a three-step synthesis of 2-methyl-2-butanol from 3-methyl-2-butanol by dragging the appropriate formulas into the bins. Note that each bin will hold only one item, and not all of the given reagents or structures will be used.

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Answer #1
Concepts and reason

To synthesize 2-methyl-2-butanol from 3-methyl-2-butanol by using the list of reagents provided.

Fundamentals

Conversion of 3-methyl-2-butanol to 2-methyl-2-butanol occurs in three steps. They are

1.Dehydration

2.Epoxidation

3.Opening of epoxide

The reaction is,

Н.РОД
Heat
ОН
3-methyl-2-butanol
2-methylbut-2-ene

The reaction is,

CH3CO3H
2,2,3-trimethyloxirane
2-methylbut-2-ene

The reaction is,

LiAlH4
OH
H20
2-methylbutan-2-ol
2,2,3-trimethyloxirane

Ans:

Thus, the three-step synthesis scheme is,

LiAlH
Н,РОД
CH,CO,Н
ОН
Heat
Н.О
ОН
2-methylbutan-2-ol
3-methylbutan-2-ol

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